Acylation stimulating protein (ASP) acute effects on postprandial lipemia and food intake in rodents
نویسندگان
چکیده
منابع مشابه
Mice lacking acylation stimulating protein (ASP) have delayed postprandial triglyceride clearance.
Acylation stimulating protein (ASP) is a 76 amino acid fragment of the third component of complement (C3) which is generated by the interaction of adipsin and factor B with C3. In vitro studies have shown that ASP can markedly increase triglyceride synthesis in adipocytes. To test the ASP pathway in vivo, C3-deficient mice, and therefore ASP-deficient mice, were generated and oral fat loads wer...
متن کامل[Effects of acute exercise on postprandial lipemia in sedentary men].
OBJECTIVE To examine the effects of a single session of isometric physical exercise on postprandial triglyceridemia in sedentary male individuals with fasting triglycerides values < 150 mg/dl (NTG) or > " 150 mg/dl (TG ALT). METHODS Twenty-seven individuals (10 NTG and 17 TG ALT), aged between 30-55 years were assessed in the study. Triglycerides were determined in the beginning, and at two, ...
متن کاملThe acylation-stimulating protein pathway and regulation of postprandial metabolism.
Much has recently been learned about the processes involved in postprandial triacylglycerol clearance. As discussed previously, important differences in the metabolism of chylomicrons and VLDL have become apparent. The ASP pathway has also been recognized and appears to play a critical role in chylomicron metabolism. The ASP pathway is activated in order to trap the fatty acids released from ch...
متن کاملAcute Effects of Exogenous Hormone Administration on Postprandial Acylation Stimulating Protein Levels in Ovariectomized Rats after a Fat Load
Background. ASP, a potent lipogenic factor, was linked to female fat metabolism in association studies. Aim. To investigate acute effects of sex hormone treatment on postprandial ASP levels in vivo. Methods. 24 female rats were randomly divided into 4 groups including controls. The rats were ovariectomized and injected with progesterone, estrogen, or testosterone. An hour later, olive oil was a...
متن کاملAcute effects of accumulating exercise on postprandial lipemia and C-reactive protein concentrations in young men.
The current study investigated the acute effects of accumulating short bouts of running on circulating concentrations of postprandial triacylglycerol (TAG) and C-reactive protein (CRP). Ten men, age 21-32 yr, completed two 1-d trials. On 1 occasion participants ran at 70% of maximum oxygen uptake in six 5-min bouts (i.e., 8:30, 10, and 11:30 a.m. and 1, 2:30, and 4 p.m.) with 85 min rest betwee...
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ژورنال
عنوان ژورنال: International Journal of Obesity
سال: 2001
ISSN: 0307-0565,1476-5497
DOI: 10.1038/sj.ijo.0801613